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- chemotherapy is given before surgery or radiation therapy , and is then called neoadjuvant therapy.
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- What Chemotherapy Can Achieve There are four possible results of chemotherapy given for visible or known areas of cancer.
- • Complete remission The tumor may seem to disappear completely, meaning that there is a complete response
- to the drugs. This clearly indicates the treatment is working, though it has to continue for a while so any
- "hidden" cancer cells will be destroyed. Current detection methods can miss an internal tumor smaller than
- 1 cm (0.4 in.), and if treatment is stopped too soon there is a high chance for a relapse.
- Some remissions, especially for very responsive tumors, may be permanent. Others are temporary, lasting
- for months or even years. But then the tumor reappears or begins to grow again. Complete remission,
- therefore, is not necessarily the same as a cure. "Cure" usually means the lack of any sign of cancer for at least
- five years, but how it's defined really depends on the kind of cancer being treated and on the individual patient.
- • Partial remission The tumor may shrink by more than half its size but not disappear. This is obviously a
- good result, but therapy has to be continued until the tumor either completely disappears or stops shrinking.
- If it simply stops shrinking, the drug program may be changed or surgery or radiotherapy may be used to try
- to wipe out the remaining tumor cells.